Category Chemistry

In the course of our research for clients, we come across emerging technologies, new materials, new chemistries, growing markets, changing regulatory landscapes, innovative business models, and much more. Every other Friday, we pick five articles, videos, or podcasts that we found interesting and send them your way.


Superconductor Boosts Lithium-Sulfur Battery Performance

Next-generation batteries based on lithium-sulfur chemistry could store more energy in lighter packages than today’s best lithium-ion batteries. But the intricacies of Li-S chemistry also limit its durability. Now researchers have found they can rein in the chemistry of Li-S cathodes by adding nanoparticles of the superconductor magnesium diboride. [C&EN]


Carbon Dioxide Emissions from the U.S. Power Sector Have Declined 28% Since 2005

Carbon dioxide emissions from the electric power sector have been on a steady decline and are now at the lowest level since 1987. Driven by low demand, state policies, and federal tax incentives encouraging the use of noncarbon electric generation like solar and wind, this decline in emissions will likely be a continuing trend. [EIA]


Lean StartUp’s Newest Tool: Innovation Accounting

A recent study of 1200 executives found that over half of them struggle with connecting their business and innovation strategies. Almost 75% believe they are not out-innovating their competition. Eric Ries, author of The Startup Way, thinks it’s because companies are measuring their progress using wild guesses; they should start using science instead. [INC]


Redefining the Kilogram

The official object that defines the mass of a kilogram is a tiny, 139-year-old cylinder of platinum and iridium that resides in a triple-locked vault near Paris. Because it is so important, scientists almost never take it out; instead they use copies called working standards. But the last time they did inspect the real kilogram, they found it slightly heavier than all the working standards, which have been leaving behind a few atoms of metal every time they are put on scales. The result: representatives from 57 countries are meeting this month to vote on a proposal to make the International System of Units fully dependent on constants of nature. The ampere, kelvin, mole, and kilogram are all expected to get new definitions. [SCIENTIFIC AMERICAN]


The 8 Best Science Images, Videos, and Visualizations of the Year

From basic principles that explain our universe, to the newest technology, science can be weird, fun, and down right exciting. But science can also be strikingly beautiful. These 8 visuals are the best this year that not only explain scientific concepts clearly, but also show just how stunning science can be. [POP SCI]

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In the course of our research for clients, we come across emerging technologies, new materials, new chemistries, growing markets, changing regulatory landscapes, innovative business models, and much more. Every other Friday, we pick five articles, videos, or podcasts that we found interesting and send them your way.


Coolest Science Ever Headed to the Space Station

On May 21, NASA’s Cold Atom Laboratory arrived at the International Space Station to explore a state of matter called a Bose-Einstein condensate (BEC), in which atoms shed their individual identities and crowd en masse into a single quantum wave. Long-predicted, but first observed in 1995, achieving the state requires chilling atoms to a fraction of a degree above absolute zero, even colder than the average temperature of deep space. Moving experiments to space solves a key challenge: being able to observe the BEC for more than 10-20 milliseconds after release from the magnets and lasers used to trap and chill the atoms. [SCIENCE]


Building a Better MVP: How to Say No to the Wrong Things So You Can Say Yes to the Right Things

The most persistent mistake companies make during product development is also one of the easiest to solve. In fact, post-mortem evaluations of over 100 startups revealed that the primary cause of startup failure—in 42% of cases—was “no market need.” How can this happen? Founders overwhelmingly said “they were more focused on solving an interesting version of the problem, rather than solving the real problem as it existed.” Don’t ignore the importance of deeply understanding the job-to-be-done: whether you are a start-up or a major corporation, get out and talk to the market. Again and again. [ALLEYWATCH]


Chemists Synthesize Millions of Proteins Not Found in Nature

In a DARPA-funded project, MIT chemists have devised a way to rapidly synthesize and screen millions of novel proteins from amino acids not used in nature; the proteins could be used as drugs against Ebola and other viruses. These “xenoproteins” offer many advantages over naturally occurring proteins: they are more stable, don’t require refrigeration, and may not provoke an immune response. Amino acids can exist in two different configurations, known as L and D, but cells can use only the L variant. As building blocks for their xenoproteins, the researchers used 16 “mirror-image” (D) amino acids. The program has already synthesized D-variant proteins that will bind to the influenza virus, the anthrax toxin, and an Ebola glycoprotein. [MIT]


Building Autonomous Vehicles is Hard

This New York Times piece describes how Apple—handicapped by hubris and a demand to control everything—has struggled to find a partner to help execute its autonomous driving ambitions. Tesla, on the other hand, is struggling with a different problem: too much vision and not enough execution. In this piece (and podcast) which originally appeared in the Harvard Business Review, Steve Blank compares Elon Musk to Billy Durant (the founder of GM who was fired twice before Alfred Sloan took over) and “wonders if $2.6 billion in executive compensation [for Musk] would be better spent finding someone to lead Tesla to becoming a reliable producer of cars in high volume – without the drama in each new model. Perhaps Tesla now needs its Alfred P. Sloan.”


Water Woes Lead EPA to Toughen Fluorochemical Rules

The EPA held an invitation-only forum in Washington last week to announce the development of tougher national regulations on the use of per- and polyfluoroalkyl substances (PFAs), and the related perfluorooctanoic acid, in an effort to keep these chemicals out of the drinking water supply. Administrator Pruitt said, “This should be and must be a national priority, and . . . we are going to be taking concrete steps as an agency to address that, along with you at the state and local level.” PFAs and PFOAs are known to persist in the environment and can pose health risks even at relatively low concentrations. Controversy plagues the EPA on this issue; it has been accused of suppressing a report suggesting the existing limits are too high and it did not open the May summit to affected community groups and activist organizations. New regulations will likely face opposition because of the importance of these chemicals across many industries. [PLASTICS NEWS]

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In the course of our research for clients across many industries and fields, we come across emerging technologies, new materials, new chemistries, growing markets, changing regulatory landscapes, innovative business models, and much more. Every other Friday, we deliver five interesting things we came across during the preceding weeks. And no filler.


In Just 4 Hours, Google’s AI Mastered All the Chess Knowledge in History

In a new paper, Google researchers detail how their latest AI evolution, AlphaZero, developed “superhuman performance” in chess, taking just four hours to learn the rules (with no strategic programming) before obliterating the world champion chess program, Stockfish. “We now know who our new overlord is,” said chess researcher David Kramaley, the CEO of chess science website Chessable, “It will no doubt revolutionize the game, but think about how this could be applied outside chess. This algorithm could run cities, continents, universes.”


Grow by Creating Markets, Versus Killing Competitors

This short summary of “Blue Ocean Shift,” W. Chan Kim and Renee Mauborgne’s update to “Blue Ocean,” describes a systematic, five-step approach to creating new markets rather than fighting to the death with your existing competitors. In our experience, the approach works, but even innovative companies struggle with Step 2: building an objective view of the strategic landscape. Their deep connection to existing markets, low risk tolerance, focus on short-term revenue pressure from investors, and rapid executive turn-over, are all factors conspiring against their ability to take the long-term view of their future necessary to build new markets from scratch. [ALLEYWATCH]


In Search of Blockchain’s Killer-Apps

“Blockchain has yet to cross the chasm from technology enthusiasts and visionaries to the wider marketplace that’s more interested in business value and applications”. Though most commonly associated with Bitcoin and other cryptocurrencies, blockchain has been getting a lot of breathless publicity for its potential to transform almost any application [we doubt it: blockchain has a massive scaling problem ]. The author speculates that two killer-app categories will benefit most from blockchain: 1. applications involving complex transactions and multiple institutions, and 2. internet security applications for identity management and data sharing. [WALL STREET JOURNAL]


Retrosynthesis: Here It Comes

Chematica—the MilliporeSigma-owned retrosynthesis software—was put to a DARPA-funded test: could the software produce a better synthesis path for eight molecules of commercial interest? The results: software 8, chemists 0. For seven of the eight targets, Chematica substantially improved synthesis routes (shorter routes, fewer chromatography steps, higher yields, more reproducible) and came from several directions (completely different synthetic approaches, different starting materials, etc.). For the eighth, it did even better, improving the synthesis but also breaking the patented route to the compound. [SCIENCE TRANSLATIONAL MEDICINE]


Newly Discovered Cellulose Could Have Applications From Energy to Medicine

A modified version of cellulose polymer was noticed in the extracellular matrix structure of e.coli . The newly identified version of cellulose does not form crystals and is readily soluble in water, making it a more suitable precursor for ethanol production. Because of its function as an extracellular matrix component, this cellulose polymer nurtures infectious bacteria, leading to a follow-on set of experiments inhibiting production of the cellulose in mice. Next stage research will involve introducing the modified cellulose genes into plants for scaled up production. [STANFORD]

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In the course of our research for clients across many industries and fields, we come across emerging technologies, new materials, new chemistries, growing markets, changing regulatory landscapes, innovative business models, and much more. Every other Friday, we deliver five interesting things we came across during the preceding weeks. And no filler.


Nokia and Vodafone Will Bring 4G to the Moon

With upcoming, non-governmental space missions delivering two new rovers to the lunar surface, Nokia and Vodafone are partnering to create a 4G base-station on the moon. The Vodafone station will use Nokia hardware to communicate more seamlessly with the rovers as well as stream high-def video back to Earth. [ENGADGET]


Investment in Lithium-ion Technologies May Crowd Out Future Innovation

This article highlights how the growth of lithium-ion-based battery infrastructure is creating technological lock-in: in spite of known thermal hazards and the impracticality of lithium-ion for powering airplanes and large trucks, chemistries beyond lithium-ion are facing higher barriers to entry and, thus, less commercial interest. The article suggests policymakers need to respond to lithium-ion lock-in by promoting research and development in high energy density alternatives, like aluminium-air or lithium-sulfur. [BROOKINGS INSTITUTION]


Lego Bricks to Be Made from Plants

Implementing a sustainability roadmap developed in 2015, the Danish manufacturer began production of Lego blocks from bio-based polyethylene. Beginning with the plant-like tree and leaf Lego pieces, the move from ABS to more sustainable materials will start small but looks to provide a different meaning and a sustainable future for “block polymers.” [CHEMICAL & ENGINEERING NEWS]


Biocomputer and Memory Built Inside Living Bacteria

Reporting on two separate feats in bioengineering, this article recaps original research in which the DNA of e.coli was manipulated to store data and, indirectly, perform basic logic functions. Researchers at Harvard archived a 36×26 pixel GIF in the e.coli DNA and then were able to retrieve the GIF with 90% efficiency and obviously recognizable form. Separately but concurrently at Harvard, a synthetic strand of DNA introduced to e.coli directed the cell to produce a RNA-based “computer” capable of basic logic and programming. [IEEE SPECTRUM]


The Five New Forces In Innovation Strategy

The article summarizes some key topics from the Drucker Forum 2017 with a focus on the five new forces outlined by Lean Start-Up pioneer Steve Blank. In addition to discussing the five forces, the article notes the importance of avoiding “innovation theater” by maintaining a healthy innovation pipeline with measured results. [FORBES]

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